MRPL43 purified MaxPab mouse polyclonal antibody (B01P)
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Specifications
Product Description
Mouse polyclonal antibody raised against a full-length human MRPL43 protein.
Immunogen
MRPL43 (NP_115488.2, 1 a.a. ~ 159 a.a) full-length human protein.
Sequence
MTARGTPSRFLASVLHNGLGRYVQQLQRLSFSVSRDGASSRGAREFVEREVIDFARRNPGVVIYVNSRPCCVPRVVAEYLNGAVREESIHCKSVEEISTLVQKLADQSGLDVIRIRKPFHTDNPSIQGQWHPFTNKPTTFRGLRPREVQDPAPAQVQAQ
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (82)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of MRPL43 expression in transfected 293T cell line (H00084545-T02) by MRPL43 MaxPab polyclonal antibody.
Lane 1: MRPL43 transfected lysate(17.49 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — MRPL43
Entrez GeneID
84545GeneBank Accession#
NM_032112Protein Accession#
NP_115488.2Gene Name
MRPL43
Gene Alias
MGC17989, MGC48892, bMRP36a
Gene Description
mitochondrial ribosomal protein L43
Gene Ontology
HyperlinkGene Summary
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. This gene and the gene for a semaphorin class 4 protein (SEMA4G) overlap at map location 10q24.31 and are transcribed in opposite directions. Sequence analysis identified multiple transcript variants encoding at least four different protein isoforms. [provided by RefSeq
Other Designations
OTTHUMP00000020304|OTTHUMP00000020305|OTTHUMP00000020307|OTTHUMP00000020310|OTTHUMP00000059154
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