SOCS6 purified MaxPab rabbit polyclonal antibody (D01P)
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More Files
- More Functions
Western Blot (Tissue lysate)
SOCS6 MaxPab rabbit polyclonal antibody. Western Blot analysis of SOCS6 expression in human liver.
Western Blot (Transfected lysate)
Western Blot analysis of SOCS6 expression in transfected 293T cell line (H00009306-T02) by SOCS6 MaxPab polyclonal antibody.
Lane 1: SOCS6 transfected lysate(59.50 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human SOCS6 protein.
Immunogen
SOCS6 (NP_004223.2, 1 a.a. ~ 535 a.a) full-length human protein.
Sequence
MKKISLKTLRKSFNLNKSKEETDFMVVQQPSLASDFGKDDSLFGSCYGKDMASCDINGEDEKGGKNRSKSESLMGTLKRRLSAKQKSKGKAGTPSGSSADEDTFSSSSAPIVFKDVRAQRPIRSTSLRSHHYSPAPWPLRPTNSEETCIKMEVRVKALVHSSSPSPALNGVRKDFHDLQSETTCQEQANSLKSSASHNGDLHLHLDEHVPVVIGLMPQDYIQYTVPLDEGMYPLEGSRSYCLDSSSPMEVSAVPPQVGGRAFPEDESQVDQDLVVAPEIFVDQSVNGLLIGTTGVMLQSPRAGHDDVPPLSPLLPPMQNNQIQRNFSGLTGTEAHVAESMRCHLNFDPNSAPGVARVYDSVQSSGPMVVTSLTEELKKLAKQGWYWGPITRWEAEGKLANVPDGSFLVRDSSDDRYLLSLSFRSHGKTLHTRIEHSNGRFSFYEQPDVEGHTSIVDLIEHSIRDSENGAFCYSRSRLPGSATYPVRLTNPVSRFMQVRSLQYLCRFVIRQYTRIDLIQKLPLPNKMKDYLQEKHY
Host
Rabbit
Reactivity
Human
Interspecies Antigen Sequence
Mouse (84); Rat (81)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
SOCS6 MaxPab rabbit polyclonal antibody. Western Blot analysis of SOCS6 expression in human liver.Western Blot (Transfected lysate)
Western Blot analysis of SOCS6 expression in transfected 293T cell line (H00009306-T02) by SOCS6 MaxPab polyclonal antibody.
Lane 1: SOCS6 transfected lysate(59.50 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — SOCS6
Entrez GeneID
9306GeneBank Accession#
NM_004232Protein Accession#
NP_004223.2Gene Name
SOCS6
Gene Alias
CIS4, HSPC060, SOCS4, SSI4, STAI4, STATI4
Gene Description
suppressor of cytokine signaling 6
Omim ID
605118Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene contains a SH2 domain and a CIS homolog domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by GM-CSF and EPO in hematopoietic cells. A high expression level of this gene was found in factor-independent chronic myelogenous leukemia (CML) and erythroleukemia (HEL) cell lines. [provided by RefSeq
Other Designations
STAT induced STAT inhibitor-4|cytokine-inducible SH2 protein 4|suppressor of cytokine signaling 4
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Interactome
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Disease
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