PTPRN2 MaxPab rabbit polyclonal antibody (D01)
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of PTPRN2 expression in transfected 293T cell line (H00005799-T04) by PTPRN2 MaxPab polyclonal antibody.
Lane 1: PTPRN2 transfected lysate(108.1 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of PTPRN2 transfected lysate using anti-PTPRN2 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with PTPRN2 purified MaxPab mouse polyclonal antibody (B01P) (H00005799-B01P).
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human PTPRN2 protein.
Immunogen
PTPRN2 (NP_570858.1, 1 a.a. ~ 986 a.a) full-length human protein.
Sequence
MGPPLPLLLLLLLLLPPRVLPAAPSSVPRGRQLPGRLGCLLEEGLCGASEACVNDGVFGRCQKVPAMDFYRYEVSPVALQRLRVALQKLSGTGFTWQDDYTQYVMDQELADLPKTYLRRPEASSPARPSKHSVGSERRYSREGGAALANALRRHLPFLEALSQAPASDVLARTHTAQDRPPAEGDDRFSESILTYVAHTSALTYPPGPRTQLREDLLPRTLGQLQPDELSPKVDSGVDRHHLMAALSAYAAQRPPAPPGEGSLEPQYLLRAPSRMPRPLLAPAAPQKWPSPLGDSEDPSSTGDGARIHTLLKDLQRQPAEVRGLSGLELDGMAELMAGLMQGVDHGVARGSPGRAALGESGEQADGPKATLRGDSFPDDGVQDDDDRLYQEVHRLSATLGGLLQDHGSRLLPGALPFARPLDMERKKSEHPESSLSSEEETAGVENVKSQTYSKDLLGQQPHSEPGAAAFGELQNQMPGPSKEEQSLPAGAQEALSDGLQLEVQPSEEEARGYIVTDREVLGPAVTFKVSANVQNVTTEDVEKATVDNKDKLEETSGLKILQTGVGSKSKLKFLPPQAEQEDSTKFIALTLVSLACILGVLLASGLIYCLRHSSQHRLKEKLSGLGGDPGADATAAYQELCRQRMATRPPDRPEGPHTSRISSVSSQFSDGPIPSPSARSSASSWSEEPVQSNMDISTGHMILSYMEDHLKNKNRLEKEWEALCAYQAEPNSSFVAQREENVPKNRSLAVLTYDHSRVLLKAENSHSHSDYINASPIMDHDPRNPAYIATQGPLPATVADFWQMVWESGCVVIVMLTPLAENGVRQCYHYWPDEGSNLYHIYEVNLVSEHIWCEDFLVRSFYLKNLQTNETRTVTQFHFLSWYDRGVPSSSRSLLDFRRKVNKCYRGRSCPIIVHCSDGAGRSGTYVLIDMVLNKMAKGAKEIDIAATLEHLRDQRPGMVQTKEQFEFALTAVAEEVNAILKALPQ
Host
Rabbit
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of PTPRN2 expression in transfected 293T cell line (H00005799-T04) by PTPRN2 MaxPab polyclonal antibody.
Lane 1: PTPRN2 transfected lysate(108.1 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of PTPRN2 transfected lysate using anti-PTPRN2 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with PTPRN2 purified MaxPab mouse polyclonal antibody (B01P) (H00005799-B01P). -
Gene Info — PTPRN2
Entrez GeneID
5799GeneBank Accession#
NM_130843.1Protein Accession#
NP_570858.1Gene Name
PTPRN2
Gene Alias
IA-2beta, IAR, ICAAR, PTPRP
Gene Description
protein tyrosine phosphatase, receptor type, N polypeptide 2
Omim ID
601698Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domain, and thus represents a receptor-type PTP. The catalytic domain of this PTP is most closely related to PTPRN/IA-2beta. This PTP and PTPRN are both found to be major autoantigens associated with insulin-dependent diabetes mellitus. Three alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported. [provided by RefSeq
Other Designations
IAR/receptor-like protein-tyrosine phosphatase|phogrin|protein tyrosine phosphatase receptor pi|tyrosine phosphatase IA-2 beta
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Interactome
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Pathway
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Disease
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