PTPRN2 purified MaxPab mouse polyclonal antibody (B01P)
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More Files
- More Functions
Western Blot (Tissue lysate)
PTPRN2 MaxPab polyclonal antibody. Western Blot analysis of PTPRN2 expression in human kidney.
Western Blot (Transfected lysate)
Western Blot analysis of PTPRN2 expression in transfected 293T cell line (H00005799-T04) by PTPRN2 MaxPab polyclonal antibody.
Lane 1: PTPRN2 transfected lysate(108.46 KDa).
Lane 2: Non-transfected lysate.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoperoxidase of purified MaxPab antibody to PTPRN2 on formalin-fixed paraffin-embedded human pancreas. [antibody concentration 3 ug/ml]
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human PTPRN2 protein.
Immunogen
PTPRN2 (NP_570858.1, 1 a.a. ~ 986 a.a) full-length human protein.
Sequence
MGPPLPLLLLLLLLLPPRVLPAAPSSVPRGRQLPGRLGCLLEEGLCGASEACVNDGVFGRCQKVPAMDFYRYEVSPVALQRLRVALQKLSGTGFTWQDDYTQYVMDQELADLPKTYLRRPEASSPARPSKHSVGSERRYSREGGAALANALRRHLPFLEALSQAPASDVLARTHTAQDRPPAEGDDRFSESILTYVAHTSALTYPPGPRTQLREDLLPRTLGQLQPDELSPKVDSGVDRHHLMAALSAYAAQRPPAPPGEGSLEPQYLLRAPSRMPRPLLAPAAPQKWPSPLGDSEDPSSTGDGARIHTLLKDLQRQPAEVRGLSGLELDGMAELMAGLMQGVDHGVARGSPGRAALGESGEQADGPKATLRGDSFPDDGVQDDDDRLYQEVHRLSATLGGLLQDHGSRLLPGALPFARPLDMERKKSEHPESSLSSEEETAGVENVKSQTYSKDLLGQQPHSEPGAAAFGELQNQMPGPSKEEQSLPAGAQEALSDGLQLEVQPSEEEARGYIVTDREVLGPAVTFKVSANVQNVTTEDVEKATVDNKDKLEETSGLKILQTGVGSKSKLKFLPPQAEQEDSTKFIALTLVSLACILGVLLASGLIYCLRHSSQHRLKEKLSGLGGDPGADATAAYQELCRQRMATRPPDRPEGPHTSRISSVSSQFSDGPIPSPSARSSASSWSEEPVQSNMDISTGHMILSYMEDHLKNKNRLEKEWEALCAYQAEPNSSFVAQREENVPKNRSLAVLTYDHSRVLLKAENSHSHSDYINASPIMDHDPRNPAYIATQGPLPATVADFWQMVWESGCVVIVMLTPLAENGVRQCYHYWPDEGSNLYHIYEVNLVSEHIWCEDFLVRSFYLKNLQTNETRTVTQFHFLSWYDRGVPSSSRSLLDFRRKVNKCYRGRSCPIIVHCSDGAGRSGTYVLIDMVLNKMAKGAKEIDIAATLEHLRDQRPGMVQTKEQFEFALTAVAEEVNAILKALPQ
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
PTPRN2 MaxPab polyclonal antibody. Western Blot analysis of PTPRN2 expression in human kidney.Western Blot (Transfected lysate)
Western Blot analysis of PTPRN2 expression in transfected 293T cell line (H00005799-T04) by PTPRN2 MaxPab polyclonal antibody.
Lane 1: PTPRN2 transfected lysate(108.46 KDa).
Lane 2: Non-transfected lysate.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoperoxidase of purified MaxPab antibody to PTPRN2 on formalin-fixed paraffin-embedded human pancreas. [antibody concentration 3 ug/ml] -
Gene Info — PTPRN2
Entrez GeneID
5799GeneBank Accession#
NM_130843Protein Accession#
NP_570858.1Gene Name
PTPRN2
Gene Alias
IA-2beta, IAR, ICAAR, PTPRP
Gene Description
protein tyrosine phosphatase, receptor type, N polypeptide 2
Omim ID
601698Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domain, and thus represents a receptor-type PTP. The catalytic domain of this PTP is most closely related to PTPRN/IA-2beta. This PTP and PTPRN are both found to be major autoantigens associated with insulin-dependent diabetes mellitus. Three alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported. [provided by RefSeq
Other Designations
IAR/receptor-like protein-tyrosine phosphatase|phogrin|protein tyrosine phosphatase receptor pi|tyrosine phosphatase IA-2 beta
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Interactome
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Pathway
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Disease
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