PTGER4 purified MaxPab rabbit polyclonal antibody (D01P)
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human PTGER4 protein.
Immunogen
PTGER4 (NP_000949.1, 1 a.a. ~ 488 a.a) full-length human protein.
Sequence
MSTPGVNSSASLSPDRLNSPVTIPAVMFIFGVVGNLVAIVVLCKSRKEQKETTFYTLVCGLAVTDLLGTLLVSPVTIATYMKGQWPGGQPLCEYSTFILLFFSLSGLSIICAMSVERYLAINHAYFYSHYVDKRLAGLTLFAVYASNVLFCALPNMGLGSSRLQYPDTWCFIDWTTNVTAHAAYSYMYAGFSSFLILATVLCNVLVCGALLRMHRQFMRRTSLGTEQHHAAAAASVASRGHPAASPALPRLSDFRRRRSFRRIAGAEIQMVILLIATSLVVLICSIPLVVRVFVNQLYQPSLEREVSKNPDLQAIRIASVNPILDPWIYILLRKTVLSKAIEKIKCLFCRIGGSRRERSGQHCSDSQRTSSAMSGHSRSFISRELKEISSTSQTLLPDLSLPDLSENGLGGRNLLPGVPGMGLAQEDTTSLRTLRISETSDSSQGQDSESVLLVDEAGGSGRAGPAPKGSSLQVTFPSETLNLSEKCI
Host
Rabbit
Reactivity
Human
Interspecies Antigen Sequence
Mouse (88); Rat (88)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
PTGER4 MaxPab rabbit polyclonal antibody. Western Blot analysis of PTGER4 expression in Jurkat.Western Blot (Transfected lysate)
Western Blot analysis of PTGER4 expression in transfected 293T cell line (H00005734-T04) by PTGER4 MaxPab polyclonal antibody.
Lane 1: PTGER4 transfected lysate(53.10 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — PTGER4
Entrez GeneID
5734GeneBank Accession#
NM_000958Protein Accession#
NP_000949.1Gene Name
PTGER4
Gene Alias
EP4, EP4R, MGC126583
Gene Description
prostaglandin E receptor 4 (subtype EP4)
Omim ID
601586Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor can activate T-cell factor signaling. It has been shown to mediate PGE2 induced expression of early growth response 1 (EGR1), regulate the level and stability of cyclooxygenase-2 mRNA, and lead to the phosphorylation of glycogen synthase kinase-3. Knockout studies in mice suggest that this receptor may be involved in the neonatal adaptation of circulatory system, osteoporosis, as well as initiation of skin immune responses. [provided by RefSeq
Other Designations
PGE receptor, EP4 subtype|prostaglandin E receptor 4, subtype EP4|prostaglandin E2 receptor
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Interactome
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Pathway
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Disease
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Publication Reference
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Abnormalities of neurotransmitter and neuropeptide systems in human neuroepithelioma cells infected by three Toxoplasma strains.
Xiao J, Li Y, Jones-Brando L, Yolken RH.
Journal of Neural Transmission 2013 Dec; 120(12):1631.
Application:WB-Ce, Human, SK-N-MC cells.
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Abnormalities of neurotransmitter and neuropeptide systems in human neuroepithelioma cells infected by three Toxoplasma strains.
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