PTGER4 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of PTGER4.
Immunogen
A synthetic peptide corresponding to 15 amino acids at C-terminus of human PTGER4.
Host
Rabbit
Reactivity
Bovine, Human, Monkey
Specificity
BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Form
Liquid
Purification
Immunoaffinity chromatography
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (2-3 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical (Formalin/PFA-fixed paraffin-embedded sections) staining in human colon, ganglion with PTGER4 polyclonal antibody (Cat # PAB26402). Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. -
Gene Info — PTGER4
Entrez GeneID
5734Protein Accession#
P35408Gene Name
PTGER4
Gene Alias
EP4, EP4R, MGC126583
Gene Description
prostaglandin E receptor 4 (subtype EP4)
Omim ID
601586Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor can activate T-cell factor signaling. It has been shown to mediate PGE2 induced expression of early growth response 1 (EGR1), regulate the level and stability of cyclooxygenase-2 mRNA, and lead to the phosphorylation of glycogen synthase kinase-3. Knockout studies in mice suggest that this receptor may be involved in the neonatal adaptation of circulatory system, osteoporosis, as well as initiation of skin immune responses. [provided by RefSeq
Other Designations
PGE receptor, EP4 subtype|prostaglandin E receptor 4, subtype EP4|prostaglandin E2 receptor
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