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PSAP (Human) IP-WB Antibody Pair

  • Catalog # : H00005660-PW2
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  • Specification
  • Product Description:
  • This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Immunoprecipitation-Western Blot (IP-WB)

    QC Testing of H00005660-PW2
    Immunoprecipitation of PSAP transfected lysate using rabbit polyclonal anti-PSAP and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-PSAP.
  • Supplied Product:
  • Antibody pair set content:
    1. Antibody pair for IP: rabbit polyclonal anti-PSAP (300 ul)
    2. Antibody pair for WB: mouse purified polyclonal anti-PSAP (50 ug)
  • Storage Instruction:
  • Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
  • Applications
  • Application Image
  • Immunoprecipitation-Western Blot
  • Gene Information
  • Entrez GeneID:
  • 5660
  • Gene Name:
  • PSAP
  • Gene Alias:
  • FLJ00245,GLBA,MGC110993,SAP1
  • Gene Description:
  • prosaposin
  • Gene Summary:
  • This gene encodes a highly conserved glycoprotein which is a precursor for 4 cleavage products: saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. Mutations in this gene have been associated with Gaucher disease, Tay-Sachs disease, and metachromatic leukodystrophy. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000019776,sphingolipid activator protein-1
  • Gene Pathway
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