OGG1 MaxPab rabbit polyclonal antibody (D01)
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More Files
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Specifications
Product Description
Rabbit polyclonal antibody raised against a full-length human OGG1 protein.
Immunogen
OGG1 (NP_058212.1, 1 a.a. ~ 324 a.a) full-length human protein.
Sequence
MPARALLPRRMGHRTLASTPALWASIPCPRSELRLDLVLPSGQSFRWREQSPAHWSGVLADQVWTLTQTEEQLHCTVYRGDKSQASRPTPDELEAVRKYFQLDVTLAQLYHHWGSVDSHFQEVAQKFQGVRLLRQDPIECLFSFICSSNNNIARITGMVERLCQAFGPRLIQLDDVTYHGFPSLQALAGPEVEAHLRKLGLGYRARYVSASARAILEEQGGLAWLQQLRESSYEEAHKALCILPGVGTKVADCICLMALDKPQAVPVDVHMWHIAQRDYSWHPTTSQAKGPSPQTNKELGNFFRSLWGPYAGWAQAVSVPRCPP
Host
Rabbit
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
OGG1 MaxPab rabbit polyclonal antibody. Western Blot analysis of OGG1 expression in Jurkat.Western Blot (Transfected lysate)
Western Blot analysis of OGG1 expression in transfected 293T cell line (H00004968-T01) by OGG1 MaxPab polyclonal antibody.
Lane 1: OGG1 transfected lysate(36.40 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of OGG1 transfected lysate using anti-OGG1 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with OGG1 MaxPab mouse polyclonal antibody (B01) (H00004968-B01). -
Gene Info — OGG1
Entrez GeneID
4968GeneBank Accession#
NM_016819.2Protein Accession#
NP_058212.1Gene Name
OGG1
Gene Alias
HMMH, HOGG1, MUTM, OGH1
Gene Description
8-oxoguanine DNA glycosylase
Gene Ontology
HyperlinkGene Summary
This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of this gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common, which contains a mitochondrial targeting signal that is essential for mitochondrial localization. Many alternative splice variants for this gene have been described, but the full-length nature for every variant has not been determined. [provided by RefSeq
Other Designations
8-hydroxyguanine DNA glycosylase|OTTHUMP00000122619
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Interactomes
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Pathways
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Diseases
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