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OGG1 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00004968-T01
  • Visit Frequency :
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  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-OGG1 full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 36.4
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-OGG1 antibody (H00004968-B01) by Western Blots.
    SDS-PAGE Gel
    QC Testing of H00004968-T01
    OGG1 transfected lysate.
    Western Blot
    QC Testing of H00004968-T01
    Lane 1: OGG1 transfected lysate ( 36.4 KDa)
    Lane 2: Non-transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 4968
  • Gene Name:
  • OGG1
  • Gene Alias:
  • HMMH,HOGG1,MUTM,OGH1
  • Gene Description:
  • 8-oxoguanine DNA glycosylase
  • Gene Summary:
  • This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of this gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common, which contains a mitochondrial targeting signal that is essential for mitochondrial localization. Many alternative splice variants for this gene have been described, but the full-length nature for every variant has not been determined. [provided by RefSeq
  • Other Designations:
  • 8-hydroxyguanine DNA glycosylase,OTTHUMP00000122619
  • Gene Pathway
  • Related Disease
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