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INS monoclonal antibody (M01), clone 3E7   

  • Catalog # : H00003630-M01
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  • 100 ug
  • USD $ 319
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    Phone : +1-909-992-0619 (new)
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against a KLH-conjugated peptide spanning 48 ~ 62 amino acid sequence of human Proinsulin.
  • Immunogen:
  • KLH-conjugated human Proinsulin peptide (NP_000198, 48 a.a. ~ 62 a.a)
  • Sequence:
  • CFFYTPKTRREAEDLQ
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Isotype:
  • IgG2a Kappa
  • Quality Control Testing:
  • Antibody Reactive Against Recombinant Protein.
  • Storage Buffer:
  • In 1x PBS, pH 7.2
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • ELISA
  • Application Image
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 3630
  • Gene Name:
  • INS
  • Gene Alias:
  • ILPR,IRDN
  • Gene Description:
  • insulin
  • Gene Summary:
  • After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into two chains (peptide A and peptide B) that are covalently linked via two disulfide bonds. Binding of this mature form of insulin to the insulin receptor (INSR) stimulates glucose uptake. A variety of mutant alleles with changes in the coding region have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000011161,OTTHUMP00000011162,OTTHUMP00000196038,proinsulin
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