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Last updated: 2014/4/21
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BIOtech
BULK-new

GSTM3 purified MaxPab mouse polyclonal antibody (B02P)MaxPab

  • Catalog # : H00002947-B02P
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  • Specification
  • Product Description:
  • Mouse polyclonal antibody raised against a full-length human GSTM3 protein.
  • Immunogen:
  • GSTM3 (NP_000840.2, 1 a.a. ~ 225 a.a) full-length human protein.
  • Sequence:
  • MSCESSMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPYLLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDHEKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLDEFPNLKAFMCRFEALEKIAAYLQSDQFCKMPINNKMAQWGNKPVC
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Antibody reactive against mammalian transfected lysate.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Western Blot analysis of GSTM3 expression in transfected 293T cell line (H00002947-T02) by GSTM3 MaxPab polyclonal antibody.

    Lane 1: GSTM3 transfected lysate(24.75 KDa).
    Lane 2: Non-transfected lysate.
  • Protocol Download
  • Detection Antibody
  • Application Image
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • Detection Antibody
  • Gene Information
  • Entrez GeneID:
  • 2947
  • Gene Name:
  • GSTM3
  • Gene Alias:
  • GST5,GSTB,GSTM3-3,GTM3,MGC3310,MGC3704
  • Gene Description:
  • glutathione S-transferase mu 3 (brain)
  • Gene Summary:
  • Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Mutations of this class mu gene have been linked with a slight increase in a number of cancers, likely due to exposure with environmental toxins. Alternative splicing results in multiple transcript variants. [provided by RefSeq
  • Other Designations:
  • GST class-mu 3,OTTHUMP00000013355,S-(hydroxyalkyl)glutathione lyase M3,brain GST,brain type mu-glutathione S-transferase,glutathione S-alkyltransferase M3,glutathione S-aralkyltransferase M3,glutathione S-aryltransferase M3,glutathione S-transferase M3 (b
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