GSTM3 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
- More Functions
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-GSTM3 full-length
Host
Human
Theoretical MW (kDa)
26.6
Interspecies Antigen Sequence
Mouse (90)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-GSTM3 antibody (H00002947-B02) by Western Blots.
SDS-PAGE Gel
GSTM3 transfected lysate.
Western Blot
Lane 1: GSTM3 transfected lysate ( 26.6 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — GSTM3
Entrez GeneID
2947GeneBank Accession#
NM_000849.3Protein Accession#
-Gene Name
GSTM3
Gene Alias
GST5, GSTB, GSTM3-3, GTM3, MGC3310, MGC3704
Gene Description
glutathione S-transferase mu 3 (brain)
Omim ID
138390Gene Ontology
HyperlinkGene Summary
Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Mutations of this class mu gene have been linked with a slight increase in a number of cancers, likely due to exposure with environmental toxins. Alternative splicing results in multiple transcript variants. [provided by RefSeq
Other Designations
GST class-mu 3|OTTHUMP00000013355|S-(hydroxyalkyl)glutathione lyase M3|brain GST|brain type mu-glutathione S-transferase|glutathione S-alkyltransferase M3|glutathione S-aralkyltransferase M3|glutathione S-aryltransferase M3|glutathione S-transferase M3 (b
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Interactome
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Pathway
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Disease
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