CLPS MaxPab mouse polyclonal antibody (B01)
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Specifications
Product Description
Mouse polyclonal antibody raised against a full-length human CLPS protein.
Immunogen
CLPS (NP_001823.1, 1 a.a. ~ 112 a.a) full-length human protein.
Sequence
MEKILILLLVALSVAYAAPGPRGIIINLENGELCMNSAQCKSNCCQHSSALGLARCTSMASENSECSVKTLYGIYYKCPCERGLTCEGDKTIVGSITNTNFGICHDAGRSKQ
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Note
For IHC and IF applications, antibody purification with Protein A will be needed prior to use.
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Applications
Western Blot (Tissue lysate)
CLPS MaxPab polyclonal antibody. Western Blot analysis of CLPS expression in human pancreas.Western Blot (Transfected lysate)
Western Blot analysis of CLPS expression in transfected 293T cell line (H00001208-T01) by CLPS MaxPab polyclonal antibody.
Lane 1: CLPS transfected lysate(12.32 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — CLPS
Entrez GeneID
1208GeneBank Accession#
NM_001832.2Protein Accession#
NP_001823.1Gene Name
CLPS
Gene Alias
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Gene Description
colipase, pancreatic
Omim ID
120105Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a cofactor needed by pancreatic lipase for efficient dietary lipid hydrolysis. It binds to the C-terminal, non-catalytic domain of lipase, thereby stabilizing an active conformation and considerably increasing the overall hydrophobic binding site. The gene product allows lipase to anchor noncovalently to the surface of lipid micelles, counteracting the destabilizing influence of intestinal bile salts. This cofactor is only expressed in pancreatic acinar cells, suggesting regulation of expression by tissue-specific elements. [provided by RefSeq
Other Designations
OTTHUMP00000016271|colipase|pancreatic colipase preproprotein
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