Western blot analysis of CAMK2D over-expressed 293 cell line, cotransfected with CAMK2D Validated Chimera RNAi ( Cat # H00000817-R01V ) (Lane 2) or non-transfected control (Lane 1). Blot probed with CAMK2D monoclonal antibody (M02) clone 1A8 (Cat # H00000817-M02 ). GAPDH ( 36.1 kDa ) used as specificity and loading control.
The product of this gene belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a delta chain. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Distinct isoforms of this chain have different expression patterns
Other Designations:
CaM kinase II delta subunit,CaM-kinase II delta chain,CaMK-II delta subunit,OTTHUMP00000163829,OTTHUMP00000163830,calcium/calmodulin-dependent protein kinase (CaM kinase) II delta,calcium/calmodulin-dependent protein kinase type II delta chain