PVR recombinant monoclonal antibody, clone 19C12
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More Files
- More Functions
Western Blot
Western Blot analysis of Lane 1: A549 whole cell lysate.
Immunohistochemistry
Immunohistochemistry image of PVR recombinant monoclonal antibody, clone 19C12 diluted at 1:50 and staining in paraffin-embedded human lung cancer performed on a Leica BondTM system.
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human PVR.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic peptide corresponding to human PVR.
Theoretical MW (kDa)
Calculated MW: 70
Reactivity
Human
Form
Liquid
Purification
Affinity chromatography purification
Isotype
IgG
Recommend Usage
ELISA
Immunohistochemistry(1:50-1:200)
Western Blot(1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH7.4 (150 mM NaCl, 0.02% sodium azide and 50% glycerol)
Storage Instruction
Store at -20°C or -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western Blot analysis of Lane 1: A549 whole cell lysate.Immunohistochemistry
Immunohistochemistry image of PVR recombinant monoclonal antibody, clone 19C12 diluted at 1:50 and staining in paraffin-embedded human lung cancer performed on a Leica BondTM system.Enzyme-linked Immunoabsorbent Assay
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Gene Info — PVR
Entrez GeneID
5817Protein Accession#
P15151Gene Name
PVR
Gene Alias
CD155, FLJ25946, HVED, NECL5, Necl-5, PVS, TAGE4
Gene Description
poliovirus receptor
Omim ID
173850Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
nectin-like 5
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Interactome
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Pathway
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Disease
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