ARG2 recombinant monoclonal antibody, clone 9A4
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human ARG2.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic peptide corresponding to human ARG2.
Reactivity
Human
Form
Liquid
Purification
Affinity chromatography purification
Isotype
IgG
Recommend Usage
ELISA
Flow Cytometry(1:50-1:200)
Immunohistochemistry(1:50-1:200)
Immunofluorescence(1:20-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH7.4 (150 mM NaCl, 0.02% sodium azide and 50% glycerol)
Storage Instruction
Store at -20°C or -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry
Immunohistochemistry image of ARG2 recombinant monoclonal antibody, clone 9A4 diluted at 1:100 and staining in paraffin-embedded human prostate cancer performed on a Leica BondTM system.Immunofluorescence
Immunofluorescence staining of PC-3 Cells with ARG2 recombinant monoclonal antibody, clone 9A4 at 1:50, counter-stained with DAPI.Enzyme-linked Immunoabsorbent Assay
Flow Cytometry
Overlay Peak curve showing PC-3 cells stained with ARG2 recombinant monoclonal antibody, clone 9A4 (red line) at 1:100. -
Gene Info — ARG2
Entrez GeneID
384Protein Accession#
P78540Gene Name
ARG2
Gene Alias
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Gene Description
arginase, type II
Omim ID
107830Gene Ontology
HyperlinkGene Summary
Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exists (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type II isoform encoded by this gene, is located in the mitochondria and expressed in extra-hepatic tissues, especially kidney. The physiologic role of this isoform is poorly understood; it is thought to play a role in nitric oxide and polyamine metabolism. Transcript variants of the type II gene resulting from the use of alternative polyadenylation sites have been described. [provided by RefSeq
Other Designations
A-II|L-arginine amidinohydrolase|L-arginine ureahydrolase|kidney arginase|nonhepatic arginase
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Interactome
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Pathway
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Disease
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