Products

Western Blot

Immunohistochemistry

Immunofluorescence

Flow Cytometry

Entrez GeneID

Protein Accession#

Gene Name

DNM2

Gene Alias

CMTDI1, CMTDIB, DI-CMTB, DYN2, DYNII

Gene Description

dynamin 2

Omim ID

Gene Ontology

Gene Summary

Dynamins represent one of the subfamilies of GTP-binding proteins. These proteins share considerable sequence similarity over the N-terminal portion of the molecule, which contains the GTPase domain. Dynamins are associated with microtubules. They have been implicated in cell processes such as endocytosis and cell motility, and in alterations of the membrane that accompany certain activities such as bone resorption by osteoclasts. Dynamins bind many proteins that bind actin and other cytoskeletal proteins. Dynamins can also self-assemble, a process that stimulates GTPase activity. Four alternatively spliced transcripts encoding different proteins have been described. Additional alternatively spliced transcripts may exist, but their full-length nature has not been determined. [provided by RefSeq

Other Designations

dynamin II