ATG4C recombinant monoclonal antibody, clone R08-8G9
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human ATG4C.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against recombinant protein corresponding to human ATG4C.
Theoretical MW (kDa)
Calculated MW: 52 kD
Reactivity
Human
Form
Liquid
Purification
Affinity chromatography
Isotype
IgG
Recommend Usage
Immunohistochemistry (1/50-1/100)
Western Blot (1/500-1/1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In 50mM Tris-Glycine, 150mM NaCl, pH 7.4 (40% glycerol, 0.05% BSA and 0.01% Sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
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Gene Info — ATG4C
Entrez GeneID
84938Protein Accession#
Q96DT6Gene Name
ATG4C
Gene Alias
APG4-C, APG4C, AUTL1, AUTL3, FLJ14867
Gene Description
ATG4 autophagy related 4 homolog C (S. cerevisiae)
Omim ID
611339Gene Ontology
HyperlinkGene Summary
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding the same protein, have been characterized. [provided by RefSeq
Other Designations
APG4 autophagy 4 homolog C|AUT-like 1, cysteine endopeptidase|AUT-like 3 cysteine endopeptidase|OTTHUMP00000010715|autophagin-3|autophagy-related cysteine endopeptidase 3
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