LIG1 recombinant monoclonal antibody, clone R02-2V6
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human DNA Ligase I.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against recombinant protein corresponding to human DNA Ligase I
Theoretical MW (kDa)
Calculated MW: 102 k
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunofluorescence (1/50-1/200)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)(1/50-1/100)
Western Blot (1/500-1/1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150 mM NaCl, pH 7.4 (50% glycerol and 0.02% Sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunocytochemistry
Immunofluorescence
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Gene Info — LIG1
Entrez GeneID
3978Gene Name
LIG1
Gene Alias
MGC117397, MGC130025
Gene Description
ligase I, DNA, ATP-dependent
Omim ID
126391Gene Ontology
HyperlinkGene Summary
LIG1 encodes DNA ligase I, with functions in DNA replication and the base excision repair process. Mutations in LIG1 that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents. [provided by RefSeq
Other Designations
DNA ligase I
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Interactome
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Pathway
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Disease
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