FLNA recombinant monoclonal antibody, clone 1B2
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More Files
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Immunohistochemistry
Immunohistochemical staining of human cervical cancer with FLNA recombinant monoclonal antibody, clone 1B2 (Cat # RAB04383) (diluated at 1:100).
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human FLNA.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic peptide corresponding to human FLNA.
Reactivity
Human
Form
Liquid
Purification
Affinity chromatography
Isotype
IgG
Recommend Usage
ELISA
Immunohistochemistry (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH7.4 (150 mM NaCl, 50% glycerol and 0.02% sodium azide)
Storage Instruction
Store at -20°C or -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry
Immunohistochemical staining of human cervical cancer with FLNA recombinant monoclonal antibody, clone 1B2 (Cat # RAB04383) (diluated at 1:100).Enzyme-linked Immunoabsorbent Assay
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Gene Info — FLNA
Entrez GeneID
2316Protein Accession#
P21333Gene Name
FLNA
Gene Alias
ABP-280, ABPX, DKFZp434P031, FLN, FLN1, FMD, MNS, NHBP, OPD, OPD1, OPD2
Gene Description
filamin A, alpha (actin binding protein 280)
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene
Other Designations
OTTHUMP00000024320|actin-binding protein 280|filamin 1|filamin A, alpha
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Interactome
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Pathway
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Disease
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