FLNA recombinant monoclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of Lane1:MCF-7 whole cell lysate Lane2:Jurkat whole cell lysate Lane3:Hela whole cell lysate Lane4:NIH/3T3 whole cell lysate with FLNA recombinant monoclonal antibody (Cat # RAB02670) at 1:1000 dilution.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human uterus tissue using FLNA recombinant monoclonal antibody (Cat # RAB02670). Counter stained with hematoxylin.
Immunocytochemistry
Immunocytochemical staining of HeLa cells using FLNA recombinant monoclonal antibody (Cat # RAB02670)(green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton *100/PBS.
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against FLNA.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against recombinant FLNA.
Theoretical MW (kDa)
280
Reactivity
Human, Mouse, Rat
Specificity
This antibody detects endogenous levels of Filamin 1 and does not cross-react with related proteins.
Form
Liquid
Purification
Protein A purification
Isotype
IgG
Recommend Usage
Flow Cytometry (1:10-1:100)
Immunocytochemistry (1:50-1:200)
Immunofluorescence (1:50-1:200)
Immunohistochemistry (1:50-1:200)
Western Blot (1:1000-1:5000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS , pH7.2 (0.02% sodium azide and 50% glycerol)
Storage Instruction
Store at 4°C short term.
Aliquot and store at -20°C long term.
Avoid freeze-thaw cycles.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of Lane1:MCF-7 whole cell lysate Lane2:Jurkat whole cell lysate Lane3:Hela whole cell lysate Lane4:NIH/3T3 whole cell lysate with FLNA recombinant monoclonal antibody (Cat # RAB02670) at 1:1000 dilution.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human uterus tissue using FLNA recombinant monoclonal antibody (Cat # RAB02670). Counter stained with hematoxylin.Immunocytochemistry
Immunocytochemical staining of HeLa cells using FLNA recombinant monoclonal antibody (Cat # RAB02670)(green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton *100/PBS.Immunofluorescence
Flow Cytometry
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Gene Info — FLNA
Entrez GeneID
2316Protein Accession#
P21333Gene Name
FLNA
Gene Alias
ABP-280, ABPX, DKFZp434P031, FLN, FLN1, FMD, MNS, NHBP, OPD, OPD1, OPD2
Gene Description
filamin A, alpha (actin binding protein 280)
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene
Other Designations
OTTHUMP00000024320|actin-binding protein 280|filamin 1|filamin A, alpha
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Interactome
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Pathway
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Disease
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