STIP1 recombinant monoclonal antibody, clone 3E4
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More Files
- More Functions
Western Blot
Western blot analysis of Lane 1: Jurkat whole cell lysate and Lane 2: K562 whole cell lysate with STIP1 recombinant monoclonal antibody, clone 3E4 (Cat # RAB04340).
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human STIP1.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic peptide corresponding to human STIP1.
Theoretical MW (kDa)
Calculated MW: 63, 6
Reactivity
Human
Form
Liquid
Purification
Affinity chromatography
Isotype
IgG
Recommend Usage
ELISA
Western Blot (1:500-1:5000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH7.4 (150mM NaCl, 50% glycerol and 0.02% sodium azide)
Storage Instruction
Store at -20 °C or -80 °C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis of Lane 1: Jurkat whole cell lysate and Lane 2: K562 whole cell lysate with STIP1 recombinant monoclonal antibody, clone 3E4 (Cat # RAB04340).Enzyme-linked Immunoabsorbent Assay
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Gene Info — STIP1
Entrez GeneID
10963Protein Accession#
P31948Gene Name
STIP1
Gene Alias
HOP, IEF-SSP-3521, P60, STI1, STI1L
Gene Description
stress-induced-phosphoprotein 1
Omim ID
605063Gene Ontology
HyperlinkGene Summary
STIP1 is an adaptor protein that coordinates the functions of HSP70 (see HSPA1A; MIM 140550) and HSP90 (see HSP90AA1; MIM 140571) in protein folding. It is thought to assist in the transfer of proteins from HSP70 to HSP90 by binding both HSP90 and substrate-bound HSP70. STIP1 also stimulates the ATPase activity of HSP70 and inhibits the ATPase activity of HSP90, suggesting that it regulates both the conformations and ATPase cycles of these chaperones (Song and Masison, 2005 [PubMed 16100115]).[supplied by OMIM
Other Designations
Hsp70/Hsp90-organizing protein|stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizing protein)
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Interactome
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Pathway
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Disease
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