LRRK2 recombinant monoclonal antibody, clone 4E9
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human LRRK2.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against recombinant protein corresponding to full length human LRRK2.
Reactivity
Human
Form
Liquid
Purification
Affinity-chromatography
Isotype
IgG
Recommend Usage
ELISA
Immunohistochemistry (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH7.4 (150 mM NaCl, 50% glycerol and 0.02% sodium azide)
Storage Instruction
Store at -20°C or -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry
Immunohistochemistry image of LRRK2 recombinant monoclonal antibody, clone 4E9 diluted at 1:100 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system.Enzyme-linked Immunoabsorbent Assay
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Gene Info — LRRK2
Entrez GeneID
120892Protein Accession#
Q5S007Gene Name
LRRK2
Gene Alias
AURA17, DARDARIN, PARK8, RIPK7, ROCO2
Gene Description
leucine-rich repeat kinase 2
Gene Ontology
HyperlinkGene Summary
This gene is a member of the leucine-rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine-rich repeat (LRR) domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in this gene have been associated with Parkinson disease-8. [provided by RefSeq
Other Designations
Parkinson disease (autosomal dominant) 8|augmented in rheumatoid arthritis 17
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Interactome
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Disease
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