S1PR1 recombinant monoclonal antibody, clone 4F2
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More Files
- More Functions
Western Blot
Western Blot analysis of Lane 1: SH-SY5Y whole cell lysate; Lane 2: PC-3 whole cell lysate; Lane 3: HepG2 whole cell lysate; Lane 4: Jurkat whole cell lysate; Lane 5: U251 whole cell lysate.
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human S1PR1.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against recombinant protein corresponding to full length human S1PR1.
Reactivity
Human
Form
Liquid
Purification
Affinity-chromatography
Isotype
IgG
Recommend Usage
ELISA
Western Blot (1:500-1:5000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH7.4 (150mM NaCl, 50% glycerol and 0.02% sodium azide)
Storage Instruction
Store at -20 °C or -80 °C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western Blot analysis of Lane 1: SH-SY5Y whole cell lysate; Lane 2: PC-3 whole cell lysate; Lane 3: HepG2 whole cell lysate; Lane 4: Jurkat whole cell lysate; Lane 5: U251 whole cell lysate.Enzyme-linked Immunoabsorbent Assay
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Gene Info — S1PR1
Entrez GeneID
1901Protein Accession#
P21453Gene Name
S1PR1
Gene Alias
CHEDG1, D1S3362, ECGF1, EDG-1, EDG1, FLJ58121, S1P1
Gene Description
sphingosine-1-phosphate receptor 1
Omim ID
601974Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is structurally similar to G protein-coupled receptors and is highly expressed in endothelial cells. It binds the ligand sphingosine-1-phosphate with high affinity and high specificity, and suggested to be involved in the processes that regulate the differentiation of endothelial cells. Activation of this receptor induces cell-cell adhesion. [provided by RefSeq
Other Designations
G protein-coupled sphingolipid receptor|OTTHUMP00000012525|endothelial differentiation, sphingolipid G-protein-coupled receptor, 1|sphingosine 1-phosphate receptor EDG1
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Interactome
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Pathway
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Disease
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