SIRT5 recombinant monoclonal antibody, clone 9H12
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human SIRT5.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against recombinant protein corresponding to full length human SIRT5.
Reactivity
Human
Form
Liquid
Purification
Affinity-chromatography
Isotype
IgG
Recommend Usage
ELISA
Immunohistochemistry (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH7.4 (150mM NaCl, 50% glycerol and 0.02% sodium azide)
Storage Instruction
store at -20 °C or -80 °C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry
Immunohistochemistry image of SIRT5 recombinant monoclonal antibody, clone 9H12 diluted at 1:100 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system.Enzyme-linked Immunoabsorbent Assay
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Gene Info — SIRT5
Entrez GeneID
23408Protein Accession#
Q9NXA8Gene Name
SIRT5
Gene Alias
FLJ36950, SIR2L5
Gene Description
sirtuin (silent mating type information regulation 2 homolog) 5 (S. cerevisiae)
Omim ID
604483Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class III of the sirtuin family. Alternative splicing of this gene results in two transcript variants. [provided by RefSeq
Other Designations
OTTHUMP00000016054|OTTHUMP00000016055|silent mating type information regulation 2, S.cerevisiae, homolog 5|sir2-like 5|sirtuin 5|sirtuin type 5
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Interactome
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Disease
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