FGB recombinant monoclonal antibody, clone 8E5
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Specification
Product Description
Mouse recombinant monoclonal antibody raised against human FGB.
Antibody Species
Mouse
Immunogen
Original antibody is raised against a synthetic β-fibrin peptide seqeunce GHRPLDKC conjugated to MB-KLH.
Reactivity
Human
Form
Liquid
Isotype
IgG1 kappa
Recommend Usage
ELISA
In vivo Imaging
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS with 0.02% Proclin 300
Storage Instruction
Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Enzyme-linked Immunoabsorbent Assay
In vivo Imaging
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Gene Info — FGB
Entrez GeneID
2244Gene Name
FGB
Gene Alias
MGC104327, MGC120405
Gene Description
fibrinogen beta chain
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency. [provided by RefSeq
Other Designations
fibrinogen, B beta polypeptide|fibrinogen, beta chain
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Disease
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