Products

Immunofluorescence

Immunofluorescent staining of Hela cells with SLC3A2 recombinant monoclonal antibody, clone HBJ127 (Cat # RAB03363).
Immunofluorescence analysis of paraformaldehyde Hela cells fixed on Shi-fix™ coverslips, permeabilized with 0.15% Triton stained with the chimeric mouse IgG1 version of RAB03363 at 10 ug/mL for 1h followed by Alexa Fluor® 488 secondary antibody (2 ug/mL), showing membrane staining. The nuclear stain is DAPI (blue). The isotype control was stained with an unknown specificity antibody followed by Alexa Fluor® 488 secondary antibody.

Enzyme-linked Immunoabsorbent Assay

Blocking

Entrez GeneID

6520

Gene Name

SLC3A2

Gene Alias

4F2, 4F2HC, 4T2HC, CD98, CD98HC, MDU1, NACAE

Gene Description

solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2

Omim ID

158070

Gene Ontology

Hyperlink

Gene Summary

This gene is a member of the solute carrier family and encodes a cell surface, transmembrane protein with an alpha amylase domain. The protein exists as the heavy chain of a heterodimer, covalently bound through di-sulfide bonds to one of several possible light chains. It associates with integrins and mediates integrin-dependent signaling related to normal cell growth and tumorigenesis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq

Other Designations

4F2 cell-surface antigen heavy chain|4F2 heavy chain|CD98 heavy chain|antigen defined by monoclonal antibody 4F2, heavy chain|antigen identified by monoclonal antibodies 4F2, TRA1.10, TROP4, and T43|heavy chain|lymphocyte activation antigen 4F2 large subu