CD3E recombinant monoclonal antibody, clone UCHT1
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More Files
- More Functions
Western Blot
Western blot anaysis anaysis of Lane1: Jurkat and Lane 2: Molt4 lysates with CD3E recombinant monoclonal antibody, clone UCHT1 (Cat # RAB03259).
Flow Cytometry
Flow cytometric analysis of human PBMCs with CD3E recombinant monoclonal antibody, clone UCHT1 (Cat # RAB03259).
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Specification
Product Description
Mouse recombinant monoclonal antibody raised against human CD3E.
Antibody Species
Mouse
Immunogen
Original antibody is raised against human infant thymocytes.
Reactivity
Human
Form
Liquid
Isotype
IgG1 kappa
Recommend Usage
Flow Cytometry
Immunohistochemistry
Western Blot
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% Proclin 300)
Storage Instruction
Store at 4°C for 3 months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot
Western blot anaysis anaysis of Lane1: Jurkat and Lane 2: Molt4 lysates with CD3E recombinant monoclonal antibody, clone UCHT1 (Cat # RAB03259).Immunohistochemistry
Flow Cytometry
Flow cytometric analysis of human PBMCs with CD3E recombinant monoclonal antibody, clone UCHT1 (Cat # RAB03259). -
Gene Info — CD3E
Entrez GeneID
916Gene Name
CD3E
Gene Alias
FLJ18683, T3E, TCRE
Gene Description
CD3e molecule, epsilon (CD3-TCR complex)
Omim ID
186830Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq
Other Designations
CD3-epsilon|CD3E antigen, epsilon polypeptide|CD3e antigen, epsilon polypeptide (TiT3 complex)|T-cell antigen receptor complex, epsilon subunit of T3|T-cell surface antigen T3/Leu-4 epsilon chain|T-cell surface glycoprotein CD3 epsilon chain
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Interactome
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Pathway
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Disease
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