JAK2 recombinant monoclonal antibody, clone JAK2Y10071008-PB6 (APC)
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More Files
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Flow Cytometry
Flow cytometric analysis of Jurkat cells untreated (red) or treated with IFNa+IL4+pervanadate (green) using Phospho-Jak2 (Tyr1007/1008) (PB6) Rabbit mAb (APC Conjugate) JAK2Y10071008-PB6, or concentration-matched Rabbit (G9) mAb IgG Isotype Control (APC Conjugate) for cells untreated (black) or treated with IFNa+IL4+pervanadate (blue).
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human JAK2.
Antibody Species
Rabbit
Immunogen
A synthetic phospho-peptide corresponding to residues surrounding Tyr1007/Tyr1008 of human phospho Jak2
Reactivity
Human
Form
Liquid
Conjugation
APC
Purification
Protein A purification, Protein G purification
Isotype
IgG
Recommend Usage
Flow Cytometry
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.2% BSA, 0.09% Sodium azide)
Storage Instruction
Store at 4°C. Do not freeze.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Flow Cytometry
Flow cytometric analysis of Jurkat cells untreated (red) or treated with IFNa+IL4+pervanadate (green) using Phospho-Jak2 (Tyr1007/1008) (PB6) Rabbit mAb (APC Conjugate) JAK2Y10071008-PB6, or concentration-matched Rabbit (G9) mAb IgG Isotype Control (APC Conjugate) for cells untreated (black) or treated with IFNa+IL4+pervanadate (blue). -
Gene Info — JAK2
Entrez GeneID
3717Protein Accession#
O60674Gene Name
JAK2
Gene Alias
JTK10
Gene Description
Janus kinase 2 (a protein tyrosine kinase)
Gene Ontology
HyperlinkGene Summary
This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis. [provided by RefSeq
Other Designations
Janus kinase 2|OTTHUMP00000021024|OTTHUMP00000043260|tyrosine-protein kinase JAK2
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Interactome
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Pathway
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Disease
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