BTK recombinant monoclonal antibody, clone BtkY223-B4 (APC)
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human BTK.
Antibody Species
Rabbit
Immunogen
A synthetic phospho-peptide corresponding to residues surrounding Tyr223 of human phospho Btk
Reactivity
Human
Form
Liquid
Purification
Protein A+G
Isotype
Rabbit IgG1k
Conjugation Note
APC
Recommend Usage
Flow Cytometry
The optimal working dilution should be determined by the end user.Storage Buffer
1X PBS, 0.09% Sodium azide, 0.2% BSA
Storage Instruction
Store at 4°C. Do not freeze.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Flow Cytometry
Flow cytometric analysis of U937 cells unstained cells negative control (blue) or untreated (red) or treated with IFNa IL4 and PV (green) using Phospho-Btk (Tyr223) B4 APC conjugated antibody BtkY223-B4. -
Gene Info — BTK
Entrez GeneID
695Protein Accession#
Q06187Gene Name
BTK
Gene Alias
AGMX1, AT, ATK, BPK, IMD1, MGC126261, MGC126262, PSCTK1, XLA
Gene Description
Bruton agammaglobulinemia tyrosine kinase
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. [provided by RefSeq
Other Designations
B-cell progenitor kinase|Bruton tyrosine kinase|OTTHUMP00000023676|OTTHUMP00000063593|agammaglobulinemia tyrosine kinase|dominant-negative kinase-deficient Brutons tyrosine kinase|tyrosine-protein kinase BTK
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Interactome
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Pathway
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Disease
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