BTK (phospho Y223) recombinant monoclonal antibody
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against BTK.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against recombinant BTK.
Theoretical MW (kDa)
77
Reactivity
Human
Specificity
This antibody detects endogenous levels of BTK protein only when phosphorylated at Tyr223.
Form
Liquid
Purification
Protein A purification
Isotype
IgG
Recommend Usage
Western Blot (1:1000-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH7.2 (50% glycerol and 0.02% sodium azide)
Storage Instruction
Store at 4°C short term.
Aliquot and store at -20°C long term.
Avoid freeze-thaw cycles.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of Lane1:K562 whole cell lysate treated with pervanadate Lane2:K562 whole cell lysate with BTK (phospho Y223) recombinant monoclonal antibody (Cat # RAB02770) at 1:1000 dilution. -
Gene Info — BTK
Entrez GeneID
695Protein Accession#
Q06187Gene Name
BTK
Gene Alias
AGMX1, AT, ATK, BPK, IMD1, MGC126261, MGC126262, PSCTK1, XLA
Gene Description
Bruton agammaglobulinemia tyrosine kinase
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. [provided by RefSeq
Other Designations
B-cell progenitor kinase|Bruton tyrosine kinase|OTTHUMP00000023676|OTTHUMP00000063593|agammaglobulinemia tyrosine kinase|dominant-negative kinase-deficient Brutons tyrosine kinase|tyrosine-protein kinase BTK
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Interactome
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