STAT6 recombinant monoclonal antibody, clone Stat3Y705-B12 (APC)
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More Files
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Flow Cytometry
Flow cytometric analysis of U937 cells unstained and untreated cells as negative control (blue) or stained and untreated (red) or treated with IFNa plus IL-4 (green) using Phospho-Stat6 (Tyr641) antibody Stat6Y641-G12 APC conjugate.
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human STAT6.
Antibody Species
Rabbit
Immunogen
A synthetic phospho-peptide corresponding to residues surrounding Tyr641 of human phospho Stat6
Reactivity
Human
Form
Liquid
Purification
Protein A+G
Isotype
Rabbit IgG1k
Conjugation Note
APC
Recommend Usage
Flow Cytometry
The optimal working dilution should be determined by the end user.Storage Buffer
1X PBS, 0.09% Sodium azide, 0.2% BSA
Storage Instruction
Store at 4°C. Do not freeze.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Flow Cytometry
Flow cytometric analysis of U937 cells unstained and untreated cells as negative control (blue) or stained and untreated (red) or treated with IFNa plus IL-4 (green) using Phospho-Stat6 (Tyr641) antibody Stat6Y641-G12 APC conjugate. -
Gene Info — STAT6
Entrez GeneID
6778Protein Accession#
P42226Gene Name
STAT6
Gene Alias
D12S1644, IL-4-STAT, STAT6B, STAT6C
Gene Description
signal transducer and activator of transcription 6, interleukin-4 induced
Omim ID
601512Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. [provided by RefSeq
Other Designations
STAT, interleukin4-induced|signal transducer and activator of transcription 6|transcription factor IL-4 STAT
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Interactome
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