CRKL recombinant monoclonal antibody, clone CrkLY207-G4
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
Western Blot
Western blot analysis of K562 cell extract untreated or treated with imatinib using 1ng/mL CrkL (Tyr207) antibody CrkLY207-G4.
Flow Cytometry
Flow cytometric analysis of K562 cells treated with imatinib (red) or treated with pervanadate (green) using Phospho-CRKL (Tyr207) (G4) Rabbit mAb CRKLY207-G4 at 0.05 ug/mL, or concentration-matched Rabbit (G9) mAb IgG Isotype Control for cells treated with imatinib (black) or treated with pervanadate (blue).
-
Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human CRKL.
Antibody Species
Rabbit
Immunogen
A synthetic phospho-peptide corresponding to residues surrounding Tyr207 of human phospho CrkL
Reactivity
Human
Form
Liquid
Purification
Protein A+G
Isotype
Rabbit IgG1k
Recommend Usage
Flow Cytometry
Western Blot
The optimal working dilution should be determined by the end user.Storage Buffer
1X PBS, 0.02% Sodium azide, 50% Glycerol, 0.1% BSA
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Western Blot
Western blot analysis of K562 cell extract untreated or treated with imatinib using 1ng/mL CrkL (Tyr207) antibody CrkLY207-G4.Flow Cytometry
Flow cytometric analysis of K562 cells treated with imatinib (red) or treated with pervanadate (green) using Phospho-CRKL (Tyr207) (G4) Rabbit mAb CRKLY207-G4 at 0.05 ug/mL, or concentration-matched Rabbit (G9) mAb IgG Isotype Control for cells treated with imatinib (black) or treated with pervanadate (blue). -
Gene Info — CRKL
Entrez GeneID
1399Protein Accession#
P46109Gene Name
CRKL
Gene Alias
-
Gene Description
v-crk sarcoma virus CT10 oncogene homolog (avian)-like
Omim ID
602007Gene Ontology
HyperlinkGene Summary
This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic
Other Designations
v-crk avian sarcoma virus CT10 oncogene homolog-like
-
Interactome
-
Pathway
-
Disease
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com