FBXO32 recombinant monoclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
Western blot analysis with FBXO32 recombinant monoclonal antibody (Cat # RAB02648) at 1:1000 dilution.
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human FBXO32.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against recombinant human FBXO32:1-200/355.
Theoretical MW (kDa)
42
Reactivity
Mouse, Rat
Specificity
This antibody detects endogenous levels of Fbx32 protein.
Form
Liquid
Purification
Protein A purification
Isotype
IgG
Recommend Usage
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In 0.01M TBS, pH7.4 (1% BSA, 0.03% Proclin300 and 50% Glycerol)
Storage Instruction
Store at 4°C short term.
Aliquot and store at -20°C long term.
Avoid freeze-thaw cycles. -
Applications
Western Blot (Tissue lysate)
Western blot analysis with FBXO32 recombinant monoclonal antibody (Cat # RAB02648) at 1:1000 dilution. -
Gene Info — FBXO32
Entrez GeneID
114907Protein Accession#
Q969P5Gene Name
FBXO32
Gene Alias
FLJ32424, Fbx32, MAFbx, MGC33610
Gene Description
F-box protein 32
Omim ID
606604Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing of this gene results in two transcript variants encoding two isoforms of different sizes. [provided by RefSeq
Other Designations
F-box only protein 32|atrogin 1|muscle atrophy F-box protein
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