ABCE1 recombinant monoclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of K562 (A), C6 (B), NIH3T3 (C), Hela (D) whole cell lysates with ABCE1 recombinant monoclonal antibody (Cat # RAB02417).
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against recombinant ABCE1.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic peptide of human ABCE1.
Theoretical MW (kDa)
68
Reactivity
Human, Mouse, Rat
Specificity
Recognizes endogenous levels of ABCE1 protein.
Form
Liquid
Purification
Immunogen affinity chromatography
Isotype
IgG
Recommend Usage
Immunoprecipitation(1:10-1:50)
Western Blot (1:500-1:1000)Storage Buffer
In 50mM Tris-Glycine, pH 7.4 (0.15M NaCl, 50% Glycerol, 0.01% Sodium azide and 0.05% BSA)
Storage Instruction
Store at 4°C short term.
Aliquot and store at -20°C long term.
Avoid freeze-thaw cycles.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of K562 (A), C6 (B), NIH3T3 (C), Hela (D) whole cell lysates with ABCE1 recombinant monoclonal antibody (Cat # RAB02417).Immunoprecipitation
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Gene Info — ABCE1
Entrez GeneID
6059Protein Accession#
P61221Gene Name
ABCE1
Gene Alias
ABC38, OABP, RLI, RNASEL1, RNASELI, RNS4I
Gene Description
ATP-binding cassette, sub-family E (OABP), member 1
Omim ID
601213Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the OABP subfamily. Alternatively referred to as the RNase L inhibitor, this protein functions to block the activity of ribonuclease L. Activation of ribonuclease L leads to inhibition of protein synthesis in the 2-5A/RNase L system, the central pathway for viral interferon action. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
Other Designations
ATP-binding cassette, sub-family E, member 1|RNase L inhibitor|ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) inhibitor
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Interactome
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Disease
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