KAT2A recombinant monoclonal antibody, clone R05-2C1
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human KAT2A.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against recombinant protein corresponding to human KAT2A.
Theoretical MW (kDa)
Calculated MW: 94 kD
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunoprecipitation (1:20)
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In 50 mM Tris-Glycine, pH 7.4 (0.15 M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA)
Storage Instruction
Store at -20 °C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western Blot analysis of K562 lysates with KAT2A recombinant monoclonal antibody, clone R05-2C1 (Cat # RAB02261).Immunoprecipitation
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Gene Info — KAT2A
Entrez GeneID
2648Protein Accession#
Q92830Gene Name
KAT2A
Gene Alias
GCN5, GCN5L2, MGC102791, PCAF-b, hGCN5
Gene Description
K(lysine) acetyltransferase 2A
Omim ID
602301Gene Ontology
HyperlinkGene Summary
KAT2A, or GCN5, is a histone acetyltransferase (HAT) that functions primarily as a transcriptional activator. It also functions as a repressor of NF-kappa-B (see MIM 164011) by promoting ubiquitination of the NF-kappa-B subunit RELA (MIM 164014) in a HAT-independent manner (Mao et al., 2009 [PubMed 19339690]).[supplied by OMIM
Other Designations
GCN5 (general control of amino-acid synthesis, yeast, homolog)-like 2|GCN5 general control of amino-acid synthesis 5-like 2|General control of amino acid synthesis, yeast, homolog-like 2
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Interactome
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Disease
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