SLC12A1 recombinant monoclonal antibody, clone R07-5D1
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human SLC12A1.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against recombinant protein corresponding to human SLC12A1.
Theoretical MW (kDa)
Calculated MW: 121 k
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In 50 mM Tris-Glycine, pH 7.4 (0.15 M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA)
Storage Instruction
Store at -20 °C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis of Hela lysates with SLC12A1 recombinant monoclonal antibody, clone R07-5D1 (Cat # RAB02058). -
Gene Info — SLC12A1
Entrez GeneID
6557Protein Accession#
Q13621Gene Name
SLC12A1
Gene Alias
BSC1, MGC48843, NKCC2
Gene Description
solute carrier family 12 (sodium/potassium/chloride transporters), member 1
Gene Ontology
HyperlinkGene Summary
The sodium-potassium-chloride cotransporter isoform 2 is kidney-specific and is found on the apical membrane of the thick ascending limb of Henle's loop and the macula densa. It accounts for most of the NaCl resorption with the stoichiometry of 1Na:1K:2Cl and is sensitive to such diuretics as furosemide and bumetanide. Some Bartter-like syndromes result from defects in this gene. [provided by RefSeq
Other Designations
NKCC2A variant A|Na-K-2Cl cotransporter|sodium potassium chloride cotransporter 2
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Interactome
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Disease
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