SLC12A1 DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a partial-length human SLC12A1 DNA using DNAx™ Immune technology.
Technology
Immunogen
Extracellular membrane domain (ECD) human DNA
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — SLC12A1
Entrez GeneID
6557GeneBank Accession#
ENST00000330289Protein Accession#
ENSP00000331550Gene Name
SLC12A1
Gene Alias
BSC1, MGC48843, NKCC2
Gene Description
solute carrier family 12 (sodium/potassium/chloride transporters), member 1
Gene Ontology
HyperlinkGene Summary
The sodium-potassium-chloride cotransporter isoform 2 is kidney-specific and is found on the apical membrane of the thick ascending limb of Henle's loop and the macula densa. It accounts for most of the NaCl resorption with the stoichiometry of 1Na:1K:2Cl and is sensitive to such diuretics as furosemide and bumetanide. Some Bartter-like syndromes result from defects in this gene. [provided by RefSeq
Other Designations
NKCC2A variant A|Na-K-2Cl cotransporter|sodium potassium chloride cotransporter 2
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Interactome
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Disease
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