WASF1 recombinant monoclonal antibody, clone R03-5K1
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More Files
- More Functions
Western Blot
Western blot analysis of Lane1: rat brain, Lane2: C6, Lane3: 3T3 and Lane4: Hela lysates with WASF1 recombinant monoclonal antibody, clone R03-5K1 (Cat # RAB01829).
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human WASF1.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against recombinant protein corresponding to human WASF1.
Theoretical MW (kDa)
Calculated MW: 62 kD
Reactivity
Human, Mouse, Rat
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In 50 mM Tris-Glycine, pH 7.4 (0.15 M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA)
Storage Instruction
Store at -20 °C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis of Lane1: rat brain, Lane2: C6, Lane3: 3T3 and Lane4: Hela lysates with WASF1 recombinant monoclonal antibody, clone R03-5K1 (Cat # RAB01829). -
Gene Info — WASF1
Entrez GeneID
8936Protein Accession#
Q92558Gene Name
WASF1
Gene Alias
FLJ31482, KIAA0269, SCAR1, WAVE, WAVE1
Gene Description
WAS protein family, member 1
Omim ID
605035Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene, a member of the Wiskott-Aldrich syndrome protein (WASP)-family, plays a critical role downstream of Rac, a Rho-family small GTPase, in regulating the actin cytoskeleton required for membrane ruffling. It has been shown to associate with an actin nucleation core Arp2/3 complex while enhancing actin polymerization in vitro. Wiskott-Aldrich syndrome is a disease of the immune system, likely due to defects in regulation of actin cytoskeleton. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000016990|Wiskott-Aldrich syndrome protein family member 1|homology of dictyostelium scar 1|verprolin homology domain-containing protein 1
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Interactome
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Pathway
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