MGST1 recombinant monoclonal antibody, clone R06-1E9
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against synthetic peptide of human Microsomal Glutathione S-transferase 1.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic peptide corresponding to human Microsomal Glutathione S-transferase 1
Theoretical MW (kDa)
Calculated MW: 18 kD
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:100)
Western Blot (1:500-1:1,000)
The optimal working dilution should be determined by the end user.Storage Buffer
In 50 mM Tris-Glycine, pH 7.4 (0.15 M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA)
Storage Instruction
Store at 4°C for short term. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis of Microsomal GST1 in rat Liver lysates using human MGST1 recombinant monoclonal antibody, clone R06-1E9 (Cat # RAB01732).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry (Formalin-fixed paraffin-embedded sections) of Human Cholangiocarcinoma with Microsomal Glutathione Stransferase 1 recombinant monoclonal antibody, clone R06-1E9 (Cat # RAB01732). -
Gene Info — MGST1
Entrez GeneID
4257Protein Accession#
P10620Gene Name
MGST1
Gene Alias
GST12, MGC14525, MGST, MGST-I
Gene Description
microsomal glutathione S-transferase 1
Omim ID
138330Gene Ontology
HyperlinkGene Summary
The MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family consists of six human proteins, two of which are involved in the production of leukotrienes and prostaglandin E, important mediators of inflammation. Other family members, demonstrating glutathione S-transferase and peroxidase activities, are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. This gene encodes a protein that catalyzes the conjugation of glutathione to electrophiles and the reduction of lipid hydroperoxides. This protein is localized to the endoplasmic reticulum and outer mitochondrial membrane where it is thought to protect these membranes from oxidative stress. Four transcript variants of this gene encode one protein isoform. [provided by RefSeq
Other Designations
glutathione S-transferase 12
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Interactome
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