MGST1 polyclonal antibody (A01)
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Specifications
Product Description
Mouse polyclonal antibody raised against a full-length recombinant MGST1.
Immunogen
MGST1 (AAH05923, 1 a.a. ~ 155 a.a) full-length recombinant protein with GST tag.
Sequence
MVDLTQVMDDEVFMAFASYATIILSKMMLMSTATAFYRLTRKVFANPEDCVAFGKGENAKKYLRTDDRVERVRRAHLNDLENIIPFLGIGLLYSLSGPDPSTAILHFRLFVGARIYHTIAYLTPLPQPNRALSFFVGYGVTLSMAYRLLKSKLYL
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (83); Rat (83)
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
ELISA
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Gene Info — MGST1
Entrez GeneID
4257GeneBank Accession#
BC005923Protein Accession#
AAH05923Gene Name
MGST1
Gene Alias
GST12, MGC14525, MGST, MGST-I
Gene Description
microsomal glutathione S-transferase 1
Omim ID
138330Gene Ontology
HyperlinkGene Summary
The MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family consists of six human proteins, two of which are involved in the production of leukotrienes and prostaglandin E, important mediators of inflammation. Other family members, demonstrating glutathione S-transferase and peroxidase activities, are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. This gene encodes a protein that catalyzes the conjugation of glutathione to electrophiles and the reduction of lipid hydroperoxides. This protein is localized to the endoplasmic reticulum and outer mitochondrial membrane where it is thought to protect these membranes from oxidative stress. Four transcript variants of this gene encode one protein isoform. [provided by RefSeq
Other Designations
glutathione S-transferase 12
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Interactomes
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Pathways
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Diseases
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Publication Reference
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Impaired cytoprotective mechanisms in eyes with pseudoexfoliation syndrome/glaucoma.
Zenkel M, Kruse FE, Naumann GO, Schlotzer-Schrehardt U.
Investigative Ophthalmology & Visual Science 2007 Dec; 48(12):5558.
Application:IF, Human, Human eyes with pseudoexfoliation (PEX) syndrome and normal control eyes.
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Impaired cytoprotective mechanisms in eyes with pseudoexfoliation syndrome/glaucoma.
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