ITGAV recombinant monoclonal antibody, clone R02-6G3
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More Files
- More Functions
Western Blot
Western blot analysis of Integrin alphaV in C6, Hela lysates using human Integrin alpha V recombinant monoclonal antibody, clone R02-6G3 (Cat # RAB01726).
Immunocytochemistry
Immunocytochemical staining of A549 with Integrin alpha V recombinant monoclonal antibody, clone R02-6G3 (Cat # RAB01726). (A) Integrin alpha V (green) and (B) DAPI (blue).
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human Integrin alpha V.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against recombinant protein corresponding to human Integrin alpha V
Theoretical MW (kDa)
Calculated MW: 116 k
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunofluorescence (1:50-1:200)
Immunoprecipitation (1:20)
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In 50 mM Tris-Glycine, pH 7.4 (0.15 M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA)
Storage Instruction
Store at 4°C for short term. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis of Integrin alphaV in C6, Hela lysates using human Integrin alpha V recombinant monoclonal antibody, clone R02-6G3 (Cat # RAB01726).Immunocytochemistry
Immunocytochemical staining of A549 with Integrin alpha V recombinant monoclonal antibody, clone R02-6G3 (Cat # RAB01726). (A) Integrin alpha V (green) and (B) DAPI (blue).Immunoprecipitation
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Gene Info — ITGAV
Entrez GeneID
3685Protein Accession#
P06756Gene Name
ITGAV
Gene Alias
CD51, DKFZp686A08142, MSK8, VNRA
Gene Description
integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)
Omim ID
193210Gene Ontology
HyperlinkGene Summary
ITAGV encodes integrin alpha chain V. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The I-domain containing integrin alpha V undergoes post-translational cleavage to yield disulfide-linked heavy and light chains, that combine with multiple integrin beta chains to form different integrins. Among the known associating beta chains (beta chains 1,3,5,6, and 8; 'ITGB1', 'ITGB3', 'ITGB5', 'ITGB6', and 'ITGB8'), each can interact with extracellular matrix ligands; the alpha V beta 3 integrin, perhaps the most studied of these, is referred to as the Vitronectin receptor (VNR). In addition to adhesion, many integrins are known to facilitate signal transduction. Alternative splicing results in multiple transcript variants. [provided by RefSeq
Other Designations
Integrin, alpha-V (vitronectin receptor, alpha polypeptide)|antigen identified by monoclonal antibody L230|integrin alpha-V
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Interactome
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Pathway
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Disease
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