COL6A1 recombinant monoclonal antibody, clone R09-8I1
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human Collagen VI.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against ecombinant protein corresponding to human Collagen VI
Theoretical MW (kDa)
Calculated MW: 109 k
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunofluorescence (1:50-1:200)
Immunohistochemistry (1:50-1/100)
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In 50 mM Tris-Glycine, pH 7.4 (0.15 M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA)
Storage Instruction
Store at 4°C for short term. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry (Frozen sections)
Immunocytochemistry
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Gene Info — COL6A1
Entrez GeneID
1291Protein Accession#
P12109Gene Name
COL6A1
Gene Alias
OPLL
Gene Description
collagen, type VI, alpha 1
Gene Ontology
HyperlinkGene Summary
The collagens are a superfamily of proteins that play a role in maintaining the integrity of various tissues. Collagens are extracellular matrix proteins and have a triple-helical domain as their common structural element. Collagen VI is a major structural component of microfibrils. The basic structural unit of collagen VI is a heterotrimer of the alpha1(VI), alpha2(VI), and alpha3(VI) chains. The alpha2(VI) and alpha3(VI) chains are encoded by the COL6A2 and COL6A3 genes, respectively. The protein encoded by this gene is the alpha 1 subunit of type VI collagen (alpha1(VI) chain). Mutations in the genes that code for the collagen VI subunits result in the autosomal dominant disorder, Bethlem myopathy. [provided by RefSeq
Other Designations
alpha 1 (VI) chain (61 AA)|collagen VI, alpha-1 polypeptide
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Interactome
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