COL6A1 polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human testis with COL6A1 polyclonal antibody (Cat # PAB30805) shows distinct positivity in collagen.
Immunofluorescence
Immunofluorescent staining of U-2 OS with COL6A1 polyclonal antibody (Cat # PAB30805) (Green) shows positivity in cytoplasm.
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human COL6A1.
Immunogen
Recombinant protein corresponding to human COL6A1.
Sequence
VSVGIKDVFDFIPGSDQLNVISCQGLAPSQGRPGLSLVKENYAELLEDAFLKNVTAQICIDKKCPDYTCPITFSSPADITILLD
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunofluorescence (1-4 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human testis with COL6A1 polyclonal antibody (Cat # PAB30805) shows distinct positivity in collagen.Immunofluorescence
Immunofluorescent staining of U-2 OS with COL6A1 polyclonal antibody (Cat # PAB30805) (Green) shows positivity in cytoplasm. -
Gene Info — COL6A1
Entrez GeneID
1291Protein Accession#
P12109Gene Name
COL6A1
Gene Alias
OPLL
Gene Description
collagen, type VI, alpha 1
Gene Ontology
HyperlinkGene Summary
The collagens are a superfamily of proteins that play a role in maintaining the integrity of various tissues. Collagens are extracellular matrix proteins and have a triple-helical domain as their common structural element. Collagen VI is a major structural component of microfibrils. The basic structural unit of collagen VI is a heterotrimer of the alpha1(VI), alpha2(VI), and alpha3(VI) chains. The alpha2(VI) and alpha3(VI) chains are encoded by the COL6A2 and COL6A3 genes, respectively. The protein encoded by this gene is the alpha 1 subunit of type VI collagen (alpha1(VI) chain). Mutations in the genes that code for the collagen VI subunits result in the autosomal dominant disorder, Bethlem myopathy. [provided by RefSeq
Other Designations
alpha 1 (VI) chain (61 AA)|collagen VI, alpha-1 polypeptide
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Interactome
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Pathway
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Disease
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