IGF1R recombinant monoclonal antibody, clone R07-7E1
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More Files
- More Functions
Western Blot
Western Blot analysis of Hela, A549, HL-60, U2OS lysates with IGF1R recombinant monoclonal antibody, clone R07-7E1 (Cat # RAB01427).
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human IGF1R.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against recombinant protein corresponding to human IGF1R.
Theoretical MW (kDa)
Calculated MW: 155 k
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Western Blot
The optimal working dilution should be determined by the end user.Storage Buffer
In 50mM Tris-Glycine, pH 7.4, (0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA)
Storage Instruction
Store at 4°C. For longer storage, aliquot and store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western Blot analysis of Hela, A549, HL-60, U2OS lysates with IGF1R recombinant monoclonal antibody, clone R07-7E1 (Cat # RAB01427).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
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Gene Info — IGF1R
Entrez GeneID
3480Protein Accession#
P08069Gene Name
IGF1R
Gene Alias
CD221, IGFIR, JTK13, MGC142170, MGC142172, MGC18216
Gene Description
insulin-like growth factor 1 receptor
Omim ID
147370Gene Ontology
HyperlinkGene Summary
This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. [provided by RefSeq
Other Designations
soluble IGF1R variant 1|soluble IGF1R variant 2
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Interactome
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Pathway
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Disease
- Abortion
- Adenocarcinoma
- Adenoma
- Alzheimer disease
- Anemia
- Aneuploidy
- Atherosclerosis
- Bacteremia
- Barrett Esophagus
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