IGF1R (phospho Tyr1166) recombinant monoclonal antibody, clone R06-6B1
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More Files
- More Functions
Western Blot
Western Blot analysis of Lane 1: C6, Lane 2: 3T3 and Lane 3: Hela lysates with IGF1R (phospho Tyr1166) recombinant monoclonal antibody, clone R06-6B1 (Cat # RAB02171).
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human IGF1R.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic phosphopeptide corresponding to residues surrounding Tyr1166 of human IGF1R.
Theoretical MW (kDa)
Calculated MW: 155 k
Reactivity
Human, Mouse, Rat
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunoprecipitation(1:20)
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In 50 mM Tris-Glycine, pH 7.4 (0.15 M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA)
Storage Instruction
Store at -20 °C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western Blot analysis of Lane 1: C6, Lane 2: 3T3 and Lane 3: Hela lysates with IGF1R (phospho Tyr1166) recombinant monoclonal antibody, clone R06-6B1 (Cat # RAB02171).Immunoprecipitation
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Gene Info — IGF1R
Entrez GeneID
3480Protein Accession#
P08069Gene Name
IGF1R
Gene Alias
CD221, IGFIR, JTK13, MGC142170, MGC142172, MGC18216
Gene Description
insulin-like growth factor 1 receptor
Omim ID
147370Gene Ontology
HyperlinkGene Summary
This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. [provided by RefSeq
Other Designations
soluble IGF1R variant 1|soluble IGF1R variant 2
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Interactome
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Pathway
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Disease
- Abortion
- Adenocarcinoma
- Adenoma
- Alzheimer disease
- Anemia
- Aneuploidy
- Atherosclerosis
- Bacteremia
- Barrett Esophagus
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