UBE2D1 recombinant monoclonal antibody, clone R07-4E8
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
Western Blot
Western Blot analysis of Raw 264.7 cells with UBE2D1 recombinant monoclonal antibody, clone R07-4E8 (Cat # RAB01363).
Western Blot
Western blot analysis of SFT in Hela, HL-60 lysates using SFT antibody.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry analysis of paraffin-embedded Human lung cancer using SFT antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
-
Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human UBE2D1.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against recombinant protein corresponding to human UBE2D1.
Theoretical MW (kDa)
Calculated MW: 17 kD
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoprecipitation
Western Blot
The optimal working dilution should be determined by the end user.Storage Buffer
In 50mM Tris-Glycine, pH 7.4, (0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA)
Storage Instruction
Store at 4°C. For longer storage, aliquot and store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Western Blot
Western Blot analysis of Raw 264.7 cells with UBE2D1 recombinant monoclonal antibody, clone R07-4E8 (Cat # RAB01363).Western Blot
Western blot analysis of SFT in Hela, HL-60 lysates using SFT antibody.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry analysis of paraffin-embedded Human lung cancer using SFT antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.Immunoprecipitation
-
Gene Info — UBE2D1
Entrez GeneID
7321Protein Accession#
P51668Gene Name
UBE2D1
Gene Alias
E2(17)KB1, SFT, UBC4/5, UBCH5, UBCH5A
Gene Description
ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast)
Omim ID
602961Gene Ontology
HyperlinkGene Summary
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is closely related to a stimulator of iron transport (SFT), and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases. [provided by RefSeq
Other Designations
OTTHUMP00000019631|stimulator of Fe transport|ubiquitin carrier protein|ubiquitin-conjugating enzyme E2-17 kDa 1|ubiquitin-conjugating enzyme E2D 1
-
Interactome
-
Pathway
-
Disease
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com