KEAP1 recombinant monoclonal antibody, clone R02-1H7
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry analysis of paraffin-embedded Human breast cancer using Keap1 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
-
Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human KEAP1.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against recombinant protein corresponding to human Keap1.
Theoretical MW (kDa)
Calculated MW: 70 kD
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Western Blot
The optimal working dilution should be determined by the end user.Storage Buffer
In 50 mM Tris-Glycine pH 7.4 (0.15 M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA)
Storage Instruction
Store at 4°C. For longer storage, aliquot and store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Western Blot
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry analysis of paraffin-embedded Human breast cancer using Keap1 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval. -
Gene Info — KEAP1
Entrez GeneID
9817Protein Accession#
Q14145Gene Name
KEAP1
Gene Alias
INrf2, KIAA0132, KLHL19, MGC10630, MGC1114, MGC20887, MGC4407, MGC9454
Gene Description
kelch-like ECH-associated protein 1
Omim ID
606016Gene Ontology
HyperlinkGene Summary
This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene. [provided by RefSeq
Other Designations
cytosolic inhibitor of Nrf2
-
Interactome
-
Pathway
-
Disease
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com