MTAP recombinant monoclonal antibody, clone MTAP/3137R
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against partial human MTAP.
Antibody Species
Rabbit
Immunogen
Recombinant protein corresponding to amino acids 97-196 of human MTAP.
Reactivity
Human
Form
Liquid
Purification
Protein A/G purification
Isotype
IgG
Recommend Usage
ELISA (Use Ab at 2-4 ug/mL for coating)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1-2 ug/mL)
Western Blot (0.5-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In 1 mg/mL PBS
Storage Instruction
Store at -20 to -80°C.
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Applications
Western Blot
Western Blot analysis of (1) HeLa, (2) A431, (3) HepG2, (4) HAP1, (5) U937 cell lysates.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human kidney.Enzyme-linked Immunoabsorbent Assay
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Gene Info — MTAP
Entrez GeneID
4507Protein Accession#
Q13126Gene Name
MTAP
Gene Alias
MSAP, c86fus
Gene Description
methylthioadenosine phosphorylase
Omim ID
156540Gene Ontology
HyperlinkGene Summary
This gene encodes an enzyme that plays a major role in polyamine metabolism and is important for the salvage of both adenine and methionine. The encoded enzyme is deficient in many cancers because this gene and the tumor suppressor p16 gene are co-deleted. Multiple alternatively spliced transcript variants have been described for this gene, but their full-length natures remain unknown. [provided by RefSeq
Other Designations
5'-methylthioadenosine phosphorylase|MeSAdo phosphorylase|OTTHUMP00000021152
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Interactome
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