PARP2 polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
PARP2 polyclonal antibody (Cat # PAB6953) (1 ug/mL) staining of human spleen Lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of PARP2.
Immunogen
A synthetic peptide corresponding to human PARP2.
Sequence
C-LDLFEVEKDGEKE
Host
Goat
Theoretical MW (kDa)
60.8
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:8000)
Western Blot (1-3 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
PARP2 polyclonal antibody (Cat # PAB6953) (1 ug/mL) staining of human spleen Lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — PARP2
Entrez GeneID
10038Protein Accession#
NP_005475.1Gene Name
PARP2
Gene Alias
ADPRT2, ADPRTL2, ADPRTL3, PARP-2, pADPRT-2
Gene Description
poly (ADP-ribose) polymerase 2
Omim ID
607725Gene Ontology
HyperlinkGene Summary
This gene encodes poly(ADP-ribosyl)transferase-like 2 protein, which contains a catalytic domain and is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. The basic residues within the N-terminal region of this protein may bear potential DNA-binding properties, and may be involved in the nuclear and/or nucleolar targeting of the protein. Two alternatively spliced transcript variants encoding distinct isoforms have been found. [provided by RefSeq
Other Designations
ADP-ribosyltransferase (NAD+; poly(ADP-ribose) polymerase)-like 2|poly (ADP-ribose) polymerase family, member 2|poly (ADP-ribosyl) transferase-like 2|poly(ADP-ribose) synthetase
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Interactome
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Pathway
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Disease
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Publication Reference
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Differential effect of PARP-2 deletion on brain injury after focal and global cerebral ischemia.
Kofler J, Otsuka T, Zhang Z, Noppens R, Grafe MR, Koh DW, Dawson VL, de Murcia JM, Hurn PD, Traystman RJ.
Journal of Cerebral Blood Flow and Metabolism 2006 Jan; 26(1):135.
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Differential effect of PARP-2 deletion on brain injury after focal and global cerebral ischemia.
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